Leaf Expression Systems is a new contract development business specialising in the expression and production of proteins, metabolites and complex natural products for research and bio-medical applications using a proprietary, transient expression technology, Hypertrans®.
Hypertrans®, developed by Prof.George Lomonossoff at the John Innes Centre, UK, allows for the simultaneous production of multiple gene products in a controlled and coordinated manner within the tissues of plants. Using gene synthesis and modular vectors, new products can be developed, validated, scaled and produced very quickly. Potential applications of the technology include:
- Production of complex proteins, such as antibodies or enzymes for research applications.
- Production of antigens including virus-like particles for vaccine development or nano-technology.
- Rapid prototyping and surge production in response to external circumstances.
- Metabolic pathway engineering to generate complex biochemicals that are difficult or impossible to synthesise chemically or are only found in rare species or trace amounts in nature.
Leaf Expression Systems is based in a purpose-built, state of the art facility to produce and engineer its feedstock plants and has industry standard downstream processing capabilities to ensure production quality and bio-security. It provides services to companies and research organisations by producing sufficient quantities of these valuable proteins and other natural products to enable research and product development.
Leaf Expression Systems
Norwich Research Park,